Dustri Online Services

Search Results

Books: 0	Journals: 1	Articles: 2

Original

The international HAE guideline under real-life conditions: From possibilities to limits in daily life – current real-world data of 8 German angioedema centers

Jens Greve, Robin Lochbaum, Susanne Trainotti, Eva-Vanessa Ebert, Thomas Buttgereit, Antonia Scherer, Lisa Knipps, Anna Smola, Sebastian Volc, Andreas Recke, Katharina Marlies Duda, Mathias Sulk, and Janina Hahn

Add to Cart ###ENGLISH_ABSTRACT_LINK### ###FREE_ENGLISH_ARTICLE_DOWNLIAD_LINK###

Volume 8 (2024) p. 346 - 357

Abstract

Allergologie select, Vol. 8/2024 (346-357)

The international HAE guideline under real-life conditions: From possibilities to limits in daily life – current real-world data of 8 German angioedema centers

Jens Greve¹, Robin Lochbaum¹, Susanne Trainotti², Eva-Vanessa Ebert², Thomas Buttgereit³, Antonia Scherer⁴, Lisa Knipps⁴,⁵, Anna Smola⁶, Sebastian Volc⁷, Andreas Recke⁸, Katharina Marlies Duda⁹, Mathias Sulk¹⁰, and Janina Hahn¹
Background and objectives: Patients with rare diseases like hereditary angioedema (HAE) are usually referred to an angioedema center to ensure guideline-compliant and experience-based therapy. Even though there are established guidelines and several approved therapeutics, there are still open questions and situations in the daily care of HAE patients, where an exchange between centers is needed. Materials and methods: A survey was conducted among physicians from German angioedema centers regarding challenges and issues in everyday HAE treatment. The main focus was on the topic of long-term prophylaxis (LTP). For rarer subcategories of angioedema, the centers conducted a literature review to discuss open questions. Results: The responses of 12 physicians from 8 angioedema centers were analyzed in the survey. The attack frequency was the most important criterion for deciding to initiate LTP in HAE patients (100%). Two centers no longer generally recommend the initiation of pre-interventional prophylaxis in HAE patients under LTP. The therapeutic concepts of acquired angioedema due to C1 inhibitor deficiency and HAE in children were two associated specialized areas that were discussed in more detail. Conclusion: The current guideline serves as the foundation for daily practice in treating HAE at specialized centers. Thus, for rare conditions like HAE, an exchange among the treating centers is essential to adequately address specific issues and rare subgroups.Correspondence to:
Prof. Dr. Jens Greve, Department of Oto-Rhino-Laryngology. Head and Neck Surgery, Ulm University Medical Center, Frauensteige 12, 89075 Ulm, Germany
Email: [email protected]

Position Paper

Recommendations on how to proceed in case of suspected allergy to penicillin/β-lactam antibiotics. Position paper of the German Society for Allergology and Clinical Immunology (DGAKI) in cooperation with the German Society for Pediatric Allergology (

Knut Brockow, Wolfgang Pfützner, Bettina Wedi, Gerda Wurpts, Axel Trautmann, Burkhard Kreft, Timo Buhl, Mathias Sulk, Andreas Recke, Kathrin Scherer, Stefan Wöhrl, Irena Neustädter, Regina Treudler, Christiane Querbach, and Margitta Worm

Add to Cart ###ENGLISH_ABSTRACT_LINK### ###FREE_ENGLISH_ARTICLE_DOWNLIAD_LINK###

Volume 9 (2025) p. 28 - 39

Abstract

Allergologie select, Vol. 9/2025 (28-39)

Knut Brockow¹, Wolfgang Pfützner², Bettina Wedi³, Gerda Wurpts⁴, Axel Trautmann⁵, Burkhard Kreft⁶, Timo Buhl⁷, Mathias Sulk⁸, Andreas Recke⁹, Kathrin Scherer¹⁰, Stefan Wöhrl¹¹, Irena Neustädter¹², Regina Treudler¹³, Christiane Querbach¹⁴, and Margitta Worm¹⁵

¹Department of Dermatology and Allergology Biederstein, Faculty of Medicine and Health, Technical University of Munich, Munich, ²Department of Dermatology and Allergology, University Hospital Giessen and Marburg, Marburg, ³Hanover Medical School, Department of Dermatology, Allergology and Venereology, Hanover, ⁴Department of Dermatology and Allergology, Germany, Aachen Comprehensive Allergy Center (ACAC), University Hospital of RWTH Aachen University, Aachen, ⁵Department of Dermatology and Allergology, Allergy Center Mainfranken, University Hospital Würzburg, Würzburg, ⁶Department of Dermatology and Venereology, University Hospital Halle, Halle (Saale), ⁷Department of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, ⁸Department of Dermatology, Münster University Hospital, Münster, ⁹Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Holstein Campus Lübeck, Lübeck, Germany, ¹⁰Department of Dermatology, Cantonal Hospital Aarau, Aarau, and Department of Dermatology and Allergology, University Hospital Basel, Switzerland, ¹¹Floridsdorf Allergy Center (FAZ), Vienna, Austria, ¹²Pediatric Clinic, Diakoneo Klinik Hallerwiese-Cnopfsche Kinderklinik, Nuremberg, ¹³Institute for Allergy Research, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, ¹⁴Hospital Pharmacy, Klinikum rechts der Isar, Technical University of Munich, Munich, and ¹⁵Allergology and Immunology, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany
β-lactam antibiotics (BLAs) are still the antibiotics of first choice for the treatment of many bacterial infections. Treatment with a BLA is often hindered by a suspected allergy, up to 10% of the population report an allergy to penicillin. After Position Paper allergological evaluation of the suspected allergic reaction to a BLA, most patients show a low probability of a BLA allergy; only in a minority of cases an allergic reaction to the repeated administration of a BLA appear likely in view of the previous history. In > 90% of cases, the suspected BLA allergy can be ruled out by allergy diagnostics. We recommend a risk-stratified approach in the context of an urgent need for BLA, which should enable most patients to receive a BLA therapy. After acute therapy, allergy diagnostics have to be done to clearly prove or reliably rule out a BLA allergy.Correspondence to:
Prof. Dr. med. Knut Brockow, Department of Dermatology and Allergology Biederstein, Faculty of Medicine and Health, Technical University of Munich, Biedersteiner Strasse 29, 80802 Munich, Germany
Email: [email protected]

Warenkorb Übersicht

Warenkorb Übersicht
Typ	Anz	Rabatt	MwSt	Preis
Der Warenkorb ist leer

Ihr Warenkorb

Search Results

Warenkorb Übersicht

Senden Sie uns eine E-Mail