Abstrakt

Cystic fibrosis is a multiple-organ disease. The severity of manifestations in the individual organs depends not only on the underlying mutation on the CFTR gene, but may also differ significantly in patients with the same mutation status. Accordingly, a number of different organ-specific therapeutic approaches exist. In most cases lung disease is a life-limiting factor and therefore is the main focus of treatment. Nevertheless, close monitoring and effective therapies for other organ manifestations are also required, because lung function may be additionally impaired due to pathological changes in other organs. Apart from the lung, mainly the pancreas, liver, gastrointestinal tract, and upper respiratory tract are affected in most patients. However, cystic fibrosis may be manifested in other organs as well, or the patient may experience damage due to extensive long-term therapy. Therapeutic measures for cystic fibrosis include drugs, diet, physiotherapy, and psychosocial approaches. The present report provides an overview of common and recent therapeutic approaches for cystic fibrosis, but with no claim to completeness.

Autoreninformation

Autoren

• J. Hammermann

Abteilungen

• UniversitätsMukoviszidoseZentrum „Christiane Herzog“, Klinik und Poliklinik für Kinder- und Jugendmedizin, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden

Adresse

Dr. med. Jutta Hammermann
UniversitätsMukoviszidoseZentrum „Christiane Herzog“
Klinik und Poliklinik für Kinder- und Jugendmedizin
Universitätsklinikum Carl Gustav Carus
Technische Universität Dresden
Fetscherstraße 74
D–01307 Dresden
Email: [email protected]

Citation