Abstrakt

Adrenaline is the drug of choice for the treatment of anaphylaxis. Up to now, intramuscular administration using an autoinjector has been recommended in national and international guidelines as the first-line treatment for anaphylaxis. Various adrenaline autoinjectors are available on the German market as emergency medication for immediate treatment by medical laypersons and specialists. Recently, a nasally administered adrenaline preparation was introduced for the first time and is available on the market. There are mainly data on healthy control subjects, which show a good adrenaline level and an expected effect on blood pressure and heart rate. To date, there is little clinical experience in the world literature for patients with anaphylaxis in children/adolescence and none in adults or from Germany. Therefore, in the following we would like to discuss theoretically the use of adrenaline via the nasal route of administration in the care of anaphylaxis patients and compare it with the intramuscular administration of adrenaline autoinjectors.

Autoreninformation

Autoren

• R. Treudler¹
• K. Brockow²
• K. Beyer^{3, 4}
• L. Klimek⁵
• L. Lange⁶
• S. Schnadt⁷
• J. Ring²
• M. Worm⁸

Abteilungen

• ¹ Institut für Allergieforschung, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin,
• ² Klinik und Poliklinik für Dermatologie und Allergologie, TUM Klinikum rechts der Isar, München,
• ³ Klinik für Pädiatrie m.S. Pneumologie, Immunologie und Intensivmedizin – Charité Universitätsmedizin Berlin, Berlin,
• ⁴ Deutsches Zentrum für Kinder- und Jugendgesundheit (DZKJ), Standort Berlin, Berlin,
• ⁵ Zentrum für Rhinologie und Allergologie, Wiesbaden,
• ⁶ Abteilung für Kinder- und Jugendmedizin, GFO Kliniken Bonn, St. Marien-Hospital, Bonn,
• ⁷ Deutscher Allergie- und Asthmabund, Möchengladbach,
• ⁸ Klinik für Dermatologie, Venerologie und Allergologie, Charité – Universitätsmedizin Berlin

Adresse

Prof. Dr. Regina Treudler
Institut für Allergieforschung
Charité – Universitätsmedizin Berlin
Hindenburgdamm 30
12203 Berlin
Email: [email protected]

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