Allergologie, Jahrgang 48 (2025) - Juli (377 - 384)

Recent findings from the anaphylaxis registry: Where are we, where do we want to go?
M. Worm, S. Dölle-Bierke, L. Faust, V. Höfer
Allergologie und Immunologie, Klinik für Dermatologie, Venerologie und Allergologie, Campus Charité Mitte, Universitätsmedizin Berlin

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DOI 10.5414/ALX02529

Abstrakt

The anaphylaxis registry collects structured data across Europe regarding triggers, accompanying circumstances, and other diseases as well as the treatment of severe allergic reactions. By March 2024, 16,988 cases had been registered, of which around 1/3 affected children and 2/3 adults. In children, males and in adults, women are most frequently affected. The most common triggers depend on age and continue to be do­minated by the food allergens in children and by insect venom in adults. The occurrence of anaphylaxis without skin symptoms is not uncommon and occurs in children in the range of 5%, regardless of the elicitor, while in adults the frequency is generally higher (up to 15%) and there are elicitor-dependent differences. The analysis of the rare food allergens that trigger anaphylaxis shows, for example, spices such as saffron and sumac and vegetables such as chicory or spring onions. One case was elicited by a mealworm. Food shows an increase in triggering anaphylaxis in children. The elicitor spectrum of foods is large and relevant due to the increasing plant-based diets. Rare allergens can cause anaphylaxis and should be further considered and monitored in the coming years to determine their frequency as elicitors of severe reactions.

Autoreninformation

Autoren

Abteilungen

  • Allergologie und Immunologie, Klinik für Dermatologie, Venerologie und Allergologie, Campus Charité Mitte, Universitätsmedizin Berlin

Adresse

Prof. Dr. med. Margitta Worm
Abteilung für Allergologie und Immunologie
Klinik für Dermatologie, Venerologie und Allergologie
Charité – Universitätsmedizin Berlin
Charitéplatz 1
10117 Berlin
Email: [email protected]

Citation

M. Worm, S. Dölle-Bierke, L. Faust und V. Höfer.Aktuelle Erkenntnisse aus dem Anaphylaxie- Register – Wo stehen wir, wo wollen wir hin?. 2025; 48: 377-384. doi: 10.5414/ALX02529.

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