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Allergologie select, Volume 5 (2021) - 1st Issue (305 - 314)

Guideline on management of suspected adverse reactions to ingested histamine - Guideline of the German Society for Allergology and Clinical Immunology (DGAKI), the Society for Pediatric Allergology and Environmental Medicine (GPA), the Medical Association
Imke Reese1, Barbara Ballmer-Weber2, Kirsten Beyer3, Sabine Dölle-Bierke4, Jörg Kleine-Tebbe5, Ludger Klimek6, Sonja Lämmel7, Ute Lepp8, Joachim Saloga9, Christiane Schäfer10, Zsolt Szepfalusi11, Regina Treudler12, Thomas Werfel13, Torsten Zuberbier14, Margitta Worm4
1 Nutrition Therapy, Munich, Germany, 2 Clinic for Dermatology and Allergology, Cantonal Hospital St. Gallen and Department of Dermatology, University Hospital Zurich, Switzerland, 3 Clinic for Pediatrics with focus on Pneumology and Immunology, Charité-Universitätsmedizin – Campus Virchow-Klinikum, Berlin, 4 Allergology and Immunology, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, 5 Allergy and Asthma Center Westend, Berlin, 6 Center for Rhinology and Allergology, Wiesbaden, 7 German Allergy and Asthma Association (DAAB), Mönchengladbach, 8 Practice for Pulmonary Medicine and Allergology, Stade, 9 Department of Dermatology, University Medical Center, Johannes Gutenberg University, Mainz, 1  0 Nutrition Therapy, Schwarzenbek, 1  1 Department of Pediatrics, Division of Pediatric Pulmonology, Allergology and Endocrinology, Comprehensive Center Pediatrics, Medical University of Vienna, Vienna, Austria, 1  2 Department of Dermatology, Venereology and Allergology, Leipzig University Medical Center, 1  3 Department of Dermatology and Allergy, Hannover Medical School, and 1  4 Comprehensive Allergy Centre Charité, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Germany

   

 

DOI 10.5414/ALX02269E

Abstract

Adverse reactions to food or food ingredients are more often perceived than objectively verifiable. However, reliable laboratory tests are often lacking. As a result, people with perceived adverse reactions to food often follow extensive elimination diets for years and unnecessarily restrict their diet, as in the case of the frequently suspected histamine intolerance. In this condition, laboratory parameters such as the determination of diamine oxidase in serum have been shown to be inconclusive. The lack of symptom reproducibility calls into question the clinical picture of adverse reactions to ingested histamine. In order to approach persons with perceived histamine intolerance and to support them in moving from blanket restrictions, which are often unnecessarily strict, to effective personalized therapeutic strategies, the present guideline of the Working Group on Food Allergy of the German Society of Allergology and Clinical Immunology (DGAKI) in cooperation with the Medical Association of German Allergists (AeDA), the Pediatric Allergology and Environmental Medicine (GPA) as well as the Swiss Society of Allergology and Immunology (SGAI) and the Austrian Society of Allergology and Immunology (ÖGAI) recommends a practicable diagnostic and therapeutic approach.

Author Details

Authors

Departments

  • 1 Nutrition Therapy, Munich, Germany,
  • 2 Clinic for Dermatology and Allergology, Cantonal Hospital St. Gallen and Department of Dermatology, University Hospital Zurich, Switzerland,
  • 3 Clinic for Pediatrics with focus on Pneumology and Immunology, Charité-Universitätsmedizin – Campus Virchow-Klinikum, Berlin,
  • 4 Allergology and Immunology, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin,
  • 5 Allergy and Asthma Center Westend, Berlin,
  • 6 Center for Rhinology and Allergology, Wiesbaden,
  • 7 German Allergy and Asthma Association (DAAB), Mönchengladbach,
  • 8 Practice for Pulmonary Medicine and Allergology, Stade,
  • 9 Department of Dermatology, University Medical Center, Johannes Gutenberg University, Mainz,
  • 1 
  • 0 Nutrition Therapy, Schwarzenbek,
  • 1 
  • 1 Department of Pediatrics, Division of Pediatric Pulmonology, Allergology and Endocrinology, Comprehensive Center Pediatrics, Medical University of Vienna, Vienna, Austria,
  • 1 
  • 2 Department of Dermatology, Venereology and Allergology, Leipzig University Medical Center,
  • 1 
  • 3 Department of Dermatology and Allergy, Hannover Medical School, and
  • 1 
  • 4 Comprehensive Allergy Centre Charité, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Germany

Address

Dr. Imke Reese, Ernährungsberatung und -therapie, Schwerpunkt Allergologie, Ansprengerstr. 19, 80803 München
Email: [email protected]

Citation

Imke Reese, Barbara Ballmer-Weber, Kirsten Beyer, Sabine Dölle-Bierke, Jörg Kleine-Tebbe, Ludger Klimek, Sonja Lämmel, Ute Lepp, Joachim Saloga, Christiane Schäfer, Zsolt Szepfalusi, Regina Treudler, Thomas Werfel, Torsten Zuberbier, and Margitta Worm.Guideline on management of suspected adverse reactions to ingested histamine - Guideline of the German Society for Allergology and Clinical Immunology (DGAKI), the Society for Pediatric Allergology and Environmental Medicine (GPA), the Medical Association. 2021; 5: 305-314. doi: 10.5414/ALX02269E.

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