Allergologie select, Volume 5 (2021) - 1st Issue (157 - 161)

Allergic bronchopulmonary aspergillosis (ABPA) in an atopic patient with difficult-to-expectorate airway secretions
Marcus Joest
Lung and Allergy Center Bonn, Germany

   

 

DOI 10.5414/ALX02200E

Abstract

In the workup of a 55-year-old atopic patient with cough and viscous secretions, we diagnosed an allergic bronchopulmonary aspergillosis (ABPA) on the basis of common diagnostic criteria for adult asthma patients (Rosenberg-Patterson and ISHAM), supported by the use of IgE antibodies against the Aspergillus components Asp f 2, f 4, and f 6. Initial treatment with prednisolone and itraconazole led to remission. In the long-term follow-up, there were few relapses until 2015, which responded well to standard treatment with oral steroids, and since 2016 the patient is in stable remission. The case highlights the valuable contribution of Aspergillus IgE measurements, including the specific IgEs against the components Asp f 1, f 2, f 4, and f 6 in the diagnosis of ABPA.

Author Details

Authors

Departments

  • Lung and Allergy Center Bonn, Germany

Address

Dr. Marcus Joest, Lungen- und Allergiezentrum Bonn, Weberstraße 118, 53113 Bonn
Email: [email protected]

Citation

Marcus Joest.Allergic bronchopulmonary aspergillosis (ABPA) in an atopic patient with difficult-to-expectorate airway secretions. 2021; 5: 157-161. doi: 10.5414/ALX02200E.

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