Int. Journal of Clinical Pharmacology and Therapeutics, Volume 38 - July (360 - 361)

Anosmia induced with alpha interferon in a patient with chronic hepatitis C
I. Kraus1, D. Vitezic2
1 Department of Gastroenterology, University Hospital Center Rijeka, Rijeka 2 Department for Science and Clinical Pharmacology, University Hospital Center Rijeka and Department of Pharmacology, University of Rijeka Medical School, Rijeka, Croatia

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DOI 10.5414/CPP38360

Abstract

This is a report of the alpha interferon-induced acute anosmia in a 37-year old patient with chronic hepatitis C. This exceptionally rare side-effect started in our patient as a smelling problem 2 weeks after the initiation of the therapy, and anosmia is still present 13 months after the discontinuation of the alpha interferon. We presume that neurotoxic mechanism could be responsible for this side-effect.

Author Details

Authors

Departments

  • 1 Department of Gastroenterology, University Hospital Center Rijeka, Rijeka
  • 2 Department for Science and Clinical Pharmacology, University Hospital Center Rijeka and Department of Pharmacology, University of Rijeka Medical School, Rijeka, Croatia

Address

Dr. I. Kraus; Department of Gastroenterology, University Hospital Center Rijeka, Kresimirova 42, 51000 Rijeka, Kroatien

Citation

I. Kraus and D. Vitezic.Anosmia induced with alpha interferon in a patient with chronic hepatitis C. 2000; 38: 360-361. doi: 10.5414/CPP38360.

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