Int. Journal of Clinical Pharmacology and Therapeutics, Volume 63 (2025) - August (398 - 402)

Treatment of severe psoriasis in a hospice care patient using secukinumab, an inhibitor of interleukin-17A expression: Treatment response and changes in quality of life

Yu Zhou1, Xueting Ma1, Hong Guo1, Shaokai Zhang2
1 Department of Dermatology, and 2 Department of Geriatrics, Changping Hospital of Traditional Chinese Medicine, Beijing, China

Add to Cart  

 

DOI 10.5414/CP204787

Abstract

Secukinumab, a fully human monoclonal antibody that antagonizes interleukin-17A (IL-17A), has proven efficacious in the management of moderate to severe plaque psoriasis. Secukinumab has established itself as an effective treatment for plaque psoriasis, offering rapid and sustained symptom improvement. However, more research is warranted to assess its efficacy and safety in elderly patients, where clinical data is currently lacking. We describe an 84-year-old female presented with stable angina pectoris needed to be hospice cared. She had more than 30 years history of plaque psoriasis. The patient underwent treatment with secukinumab for two weeks. The skin lesions had been decreased rapidly and this greatly improved quality life of this patient. We report the clinical use of secukinumab in the treatment of elderly psoriasis and biologicals may be a new strategy for hospice care of patients with psoriasis.

Author Details

Authors

Departments

  • 1 Department of Dermatology, and
  • 2 Department of Geriatrics, Changping Hospital of Traditional Chinese Medicine, Beijing, China

Address

Yu Zhou, PhD
Department of Dermatology
Changping District Hospital of Traditional Chinese Medicine
No. 140 Donghuan Road, Changping District
Beijing,102200, China
Email: [email protected]

Citation

Yu Zhou, Xueting Ma, Hong Guo, Shaokai Zhang.Treatment of severe psoriasis in a hospice care patient using secukinumab, an inhibitor of interleukin-17A expression: Treatment response and changes in quality of life
. Int J Clin Pharmacol Ther. 2025; 63: 398-402. doi: 10.5414/CP204787. Pubmed: https://pubmed.ncbi.nlm.nih.gov/40329840/; PMID: 40329840.

###article_not_exists_msg###

Shopping Overview

Shopping Overview
Type Qtty Discount VAT Price
Your basket is empty
View Cart