Abstract

The concomitant existence of a non-malignant neuroendocrine tumor (NET) and membranous glomerulonephritis (MGN) is rare. We report a subject with kidney biopsy proven MGN and nephrotic syndrome in which a computerized scan tomography (CT) examination was performed revealing a pancreatic tumor. A pancreatectomy was performed and the tumor was shown to be a non-malignant NET with a malignant potential. Although treatment with corticosteroids was initiated remission of MGN was observed within the next month after pancreatectomy. The rapid remission observed shortly after pancreatectomy pointed to that tumor removal contributed to, and that neither spontaneous nor corticosteroid treatment alone did induce the rapid remission of the MGN. The coexistence of the two disorders NET and MGN is very rare, however. This is the first report on remission of MGN after pancreatectomy for a NET.

Author Details

Authors

• T. Forslund¹
• I. Kellokumpu²
• E. Elomaa³
• J. Arola⁴
• K. Nuorva⁵

Departments

• ¹ Division of Nephrology, Department of Internal Medicine,
• ² Department of Abdominal Surgery,
• ³ Department of Clinical Radiology, Central Finland Health Care District Hospital, Jyväskylä,
• ⁴ Department of Pathology, University of Helsinki and HUSLAB, Helsinki, and
• ⁵ Department of Pathology, Central Finland Health Care District Hospital, Jyväskylä, Finland

Address

T. Forslund, MD, PhD, Associate Professor
Division of Nephrology, Department of Medicine
Central Finland Health Care District Hospital
40620 Jyväskylä, Finland
Email: [email protected]

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