Abstract

Hemodialysis is the extracorporeal treatment of choice for various life-threatening intoxications, with the exception of highly protein-bound substances, which are preferably removed by charcoal hemoperfusion. This technique, however, is limited by its availability and its significant side effects. We present a potentially lifethreatening diphenhydramine (DPH) overdose in a stuporous female patient in which high cut-off hemodialysis was used. Timely detoxification resulted in rapid gain of consciousness, allowing the patient to state the existence and location of another poison victim.

Author Details

Authors

• Eva Baroke¹
• Julius J. Schmidt²
• Ann-Kathrin Strunk²
• Olaf Wiesner¹
• W. Nikolaus Kühn-Velten³
• Jan T. Kielstein²

Departments

• ¹ Department of Pulmonary Medicine,
• ² Department of Nephrology and Hypertension, Hannover Medical School, Hannover, and
• ³ Medical Laboratory, Bremen, Germany

Address

Jan T. Kielstein, MD
Department of Internal Medicine
Division of Nephrology and Hypertension
Medical School Hannover
Carl-Neuberg-Strasse 1, 30625 Hannover, Germany
Email: [email protected]

Log in for Subscribers

Citation