Abstract

Objective: Due to limited economic conditions, we tried to provide “fitted” dialysis doses instead of the doses recommended by the international guidelines to the individual patients. In the present cross-sectional study, we studied the dialysis adequacy and nutritional status of 5 peritoneal dialysis patients who had a low dialysis dose (2 bags, 4,000 mL/day). Methods: The 3-day dietary records were reviewed to calculate patients’ energy, protein, and nitrogen intake (NI). The nitrogen removal (NR) from urine and dialysate was measured by Kjeldahl technique. Fecal nitrogen was estimated as 0.0155 g/kg/day. Subjective global nutritional assessment was used to evaluate the nutritional status. Results: Among the 5 patients, 1 male and 4 female, mean age was 59 (42 – 81) years, dialysis duration 43 (33 – 74) months, body weight 51.05 ± 2.53 kg. The mean dietary protein intake was 0.66 g/kg/day, total weekly Kt/v was 1.25 (residual kidney Kt/v was 0.09), and total daily fluid removal was 699 mL. However, they achieved lower-level neutral nitrogen balance (NI 5.26 ± 0.93 g/day vs. NR 5.33 ± 0.81 g/day, N balance –0.07 ± 0.60 g/day). All of them maintained good nutritional status (SGA “A”) without symptoms of nitrogen retention (serum urea 22 ± 4.18 mmol/L). Conclusions: Lower dialysis dose with lower daily protein intake can achieve a lower-level nitrogen balance and does not lead to malnutrition. It may be an effective approach to solve the dialysis problem for the economically week population in China, especially for people with a smaller body size with lower transport membrane.


Author Details

Authors

• Chun-yan Su¹,²
• Tao Wang²
• Xin-hong Lu²
• Sha Ma²
• Wen Tang²
• Pei-yu Wang¹

Departments

• ¹ Department of Nutrition, Food Hygiene, School of Public Health, Peking University, Beijing,
• ² Division of Nephrology, Peking University Third Hospital, Beijing, China

Address

Pei-yu Wang, PhD
Department of Nutrition and Food Hygiene
School of Public Health, Peking University,
38 Xueyuan Road, Haidian District,
Beijing, 100191 China

Email: [email protected]

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