Abstract

Bile acid nephropathy also known as cholemic nephropathy is a rare and overlooked form of acute kidney injury that occurs in the setting of severe hyperbilirubinemia. The exact etiology remains unknown, and there is a lack of treatment guidelines for this clinical condition. Anabolic steroids are known to cause hepatoxicity occasionally leading to acute kidney injury. We report the case of a 27-year-old male patient who developed bile acid nephropathy as a result of severe hyperbilirubinemia secondary to anabolic steroids-induced liver injury. He was conservatively managed. We review the current literature touching on the etiology, pathophysiology, diagnosis, and management of bile acid nephropathy in an attempt to shed light on this clinical condition, which may present as a diagnostic and therapeutic challenge.

Author Details

Authors

• Hamdan Al Awadhi¹
• Sarah Al Qassimi¹
• Aya Akhras¹
• Leal Herlitz²
• Muriel Ghosn³

Departments

• ¹ Division of Internal Medicine, Department of Medicine, Cleveland Clinic Abu Dhabi Hospital, Abu Dhabi, UAE,
• ² Department of Pathology, Cleveland Clinic, Cleveland, Ohio, USA, and
• ³ Division of Nephrology, Department of Medicine, Cleveland Clinic Abu Dhabi Hospital, Abu Dhabi, UAE

Address

Muriel Ghosn, MD, Cleveland Clinic Abu Dhabi Hospital, Al Maryah Island, P.O. Box 112412, Abu Dhabi, UAE
Email: [email protected]

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